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Structure paper

TitleStructural basis of Irgb6 inactivation by Toxoplasma gondii through the phosphorylation of switch I
Journal, issue, pagesTo Be Published
Publish dateOct 10, 2022 (structure data deposition date)
AuthorsOkuma, H. / Saijo-Hamano, Y. / Sherif, A.A. / Hashizaki, E. / Sakai, N. / Kato, K. / Imasaki, T. / Nitta, E. / Sasai, M. / Kosako, H. ...Okuma, H. / Saijo-Hamano, Y. / Sherif, A.A. / Hashizaki, E. / Sakai, N. / Kato, K. / Imasaki, T. / Nitta, E. / Sasai, M. / Kosako, H. / Standley, D.M. / Yamamoto, M. / Nitta, R.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.68 - 2.05 Å
Structure data

PDB-8h4m:
Crystal Structure of GTP-bound Irgb6_T95D mutant
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

PDB-8h4o:
Crystal Structure of nucleotide-free Irgb6_T95D mutant
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Toxoplasma gondii / PV / IRG / GTPase / HYDROLASE

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