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Structure paper

TitleDCLK1 Autoinhibition and Activation in Tumorigenesis
Journal, issue, pagesInnovation (N Y), Year 2021
Publish dateSep 20, 2019 (structure data deposition date)
AuthorsCheng, L. / Yang, Z. / Guo, W. / Wu, C. / Liang, S. / Tong, A. / Cao, Z. / Thorne, R.F. / Yang, S.Y. / Yu, Y. / Chen, Q.
External linksInnovation (N Y) / Search PubMed
MethodsX-ray diffraction
Resolution2.141 - 2.206 Å
Structure data

PDB-6kyq:
Crystal structure of DCLK1 Autoinhibited Kinase Domain
Method: X-RAY DIFFRACTION / Resolution: 2.141 Å

PDB-6kyr:
Crystal structure of DCLK1 mutant (P675L) Autoinhibited Kinase Domain
Method: X-RAY DIFFRACTION / Resolution: 2.206 Å

Chemicals

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / kinase / autoinhibition

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