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TitleStructure of Geobacillus stearothermophilus Cas9: Insights into the Catalytic Process and Thermostability of CRISPR-Cas9
Journal, issue, pagesAcs Catalysis, Vol. 14, Page 13227-13235, Year 2024
Publish dateJun 21, 2023 (structure data deposition date)
AuthorsShen P / Zhang L / Liu B / Li X / Wang C / Min J / Huang JW / Chen CC / Guo RT
External linksAcs Catalysis / Search PubMed
MethodsEM (single particle)
Resolution3.08 - 3.21 Å
Structure data

36646

8jtj

EMDB-36646, PDB-8jtj:
Cryo-EM structure of GeoCas9-sgRNA-dsDNA ternary complex
Method: EM (single particle) / Resolution: 3.08 Å

36650

8jtr

EMDB-36650, PDB-8jtr:
Cryo-EM structure of GeoCas9-sgRNA binary complex
Method: EM (single particle) / Resolution: 3.21 Å

Source
  • geobacillus stearothermophilus (bacteria)
KeywordsDNA BINDING PROTEIN/RNA/DNA / RNA-binding / DNA-binding / complex / DNA BINDING PROTEIN-RNA-DNA complex / RNA BINDING PROTEIN/RNA / Gene editing / CRISPR-Cas system / RNA BINDING PROTEIN-RNA complex

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