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Structure paper

TitleMetal induced structural changes observed in Human insulin
Journal, issue, pagesTo be Published
Publish dateAug 21, 2009 (structure data deposition date)
AuthorsRaghavendra, N. / Pattabhi, V. / Rajan, S.S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-3ir0:
Crystal Structure of Human Insulin complexed with Cu+2 metal ion
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CU:
COPPER (II) ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE / Insulin / metal binding / Coordination / Confromation / Bilogical role / Carbohydrate metabolism / Cleavage on pair of basic residues / Diabetes mellitus / Disease mutation / Disulfide bond / Glucose metabolism / Secreted

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