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Structure paper

TitleStructure of tubulin and nitrogen-containing heterocyclic substituted podophyllotoxin derivatives complex
Journal, issue, pagesTo Be Published
Publish dateJul 27, 2024 (structure data deposition date)
AuthorsBi, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3.48 Å
Structure data

PDB-9ixb:
Structure of tubulin and nitrogen-containing heterocyclic substituted podophyllotoxin derivatives complex
Method: X-RAY DIFFRACTION / Resolution: 3.48 Å

Chemicals

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-MG:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

PDB-1ecq:
E. COLI GLUCARATE DEHYDRATASE BOUND TO 4-DEOXYGLUCARATE

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-IMD:
IMIDAZOLE

ChemComp-ACP:
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER / AMP-PCP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
  • gallus gallus (chicken)
  • sus scrofa (pig)
KeywordsCELL CYCLE / tublin / GTP / inhibitor / two binding sites

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