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| Title | Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS |
|---|---|
| Journal, issue, pages | To be Published |
| Publish date | Apr 14, 2009 (structure data deposition date) |
Authors | Seetharaman, S.V. / Winkler, D.D. / Taylor, A.B. / Cao, X. / Whitson, L.J. / Doucette, P.A. / Valentine, J.S. / Carroll, M.C. / Culotta, V.C. / Hart, P.J. |
External links | Search PubMed |
| Methods | X-ray diffraction |
| Resolution | 1.55 - 1.85 Å |
| Structure data | ![]() PDB-3h2p: ![]() PDB-3h2q: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-MLI: ![]() ChemComp-ACE: ![]() ChemComp-HOH: ![]() ChemComp-SO4: |
| Source |
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Keywords | OXIDOREDUCTASE / human cu / zn superoxide dismutase / antioxidant / metal-binding / copper / zinc / amyotrophic lateral sclerosis / disease mutation / Acetylation / Cytoplasm / Disulfide bond / Phosphoprotein / Ubl conjugation |
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homo sapiens (human)
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