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TitleCrystal Structure Of O-Acetylserine Sulfhydrylase From Haemophilus Influenzae In Complex With Pre-Reactive O-Acetyl Serine, Alpha-Aminoacrylate Reactionintermediate And Peptide Inhibitor At The Resolution Of 2.25A
Journal, issue, pagesTo Be Published
Publish dateAug 21, 2015 (structure data deposition date)
AuthorsSingh, A.K. / Kaushik, A. / Ekka, M.K. / Kumaran, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-5dbe:
Crystal structure of O-acetylserine sulfhydrylase from Haemophilus influenzae in complex with pre-reactive O-acetyl serine, alpha-aminoacrylate reaction intermediate and peptide inhibitor at the resolution of 2.25A
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-OAS:
O-ACETYLSERINE

ChemComp-0JO:
2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid

ChemComp-HOH:
WATER

Source
  • haemophilus influenzae kw20 (bacteria)
  • salmonella typhimurium lt2 (bacteria)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / AMINO-ACID BIOSYNTHESIS / CYSTEINE BIOSYNTHESIS / TRANSFERASE / PYRIDOXAL PHOSPHATE / TRANSFERASE-TRANSFERASE INHIBITOR COMP / TRANSFERASE-TRANSFERASE INHIBITOR complex

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