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TitleCrystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe
Journal, issue, pagesTo Be Published
Publish dateDec 20, 2015 (structure data deposition date)
AuthorsTallant, C. / Owen, D.R. / Gerstenberger, B.S. / Savitsky, P. / Chaikuad, A. / Fedorov, O. / Nunez-Alonso, G. / Filippakopoulos, P. / von Delft, F. / Arrowsmith, C.H. ...Tallant, C. / Owen, D.R. / Gerstenberger, B.S. / Savitsky, P. / Chaikuad, A. / Fedorov, O. / Nunez-Alonso, G. / Filippakopoulos, P. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Bountra, C. / Muller, S. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.1 Å
Structure data

PDB-5fg6:
Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe
Method: X-RAY DIFFRACTION / Resolution: 1.1 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-5XE:
4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide

ChemComp-NI:
NICKEL (II) ION

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / MOZ-MORF complex

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