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TitleTargeting the Mannitol Biosynthesis Pathway in Aspergillus fumigatus: Characterisation and Inhibition of Mannitol-2-Dehydrogenase
Journal, issue, pagesTo Be Published
Publish dateJul 22, 2021 (structure data deposition date)
AuthorsNguyen, S. / Jovcevski, B. / Pukala, T.L. / Bruning, J.B.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 - 2.1 Å
Structure data

PDB-7rk4:
Mannitol-2-dehydrogenase from Aspergillus fumigatus
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-7rk5:
Mannitol-2-dehydrogenase bound to NADH from Aspergillus fumigatus
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAI:
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

Source
  • neosartorya fumigata (strain atcc mya-4609 / af293 / cbs 101355 / fgsc a1100) (mold)
KeywordsOXIDOREDUCTASE / mannitol biosynthesis

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