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-Structure paper
タイトル | Human prostaglandin/alkenal reductases: substrate specificities, inhibitor profiles, structural insights and subcellular localization suggest protective roles in inflammatory and oxidative stress conditions. |
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ジャーナル・号・ページ | To Be Published |
掲載日 | 2022年3月31日 (構造データの登録日) |
![]() | Shafqat, N. / Dakin, S.G. / Estrada, F.M. / Niesen, F.H. / Wells, G. / Yapp, C. / Troumpra, M.K. / Brotherton, D. / Porte, S. / Mesa, J. ...Shafqat, N. / Dakin, S.G. / Estrada, F.M. / Niesen, F.H. / Wells, G. / Yapp, C. / Troumpra, M.K. / Brotherton, D. / Porte, S. / Mesa, J. / Yakovtseva, E. / Farres, J. / Pares, X. / Liu, T. / Altman, R. / Carr, A. / Koekemoer, L. / Niesen, F. / Yue, W.W. / Opperman, U. |
![]() | PubMedで検索 |
手法 | X線回折 |
解像度 | 1.79 Å |
構造データ | ![]() PDB-7zej: |
化合物 | ![]() ChemComp-NAP: ![]() ChemComp-CEL: ![]() ChemComp-HOH: |
由来 |
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![]() | OXIDOREDUCTASE / alkenal reductases / prostaglandin reductases / phase 1 xenobiotic metabolism / reactive oxygen species / lipid peroxidation / polyunsaturated fatty acid / inflammation / lipid mediator metabolism / Structural Genomics / Structural Genomics Consortium / SGC |