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TitleCryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the short-lived asymmetric pre-active state
Journal, issue, pagesTo Be Published
Publish dateMay 23, 2024 (structure data deposition date)
AuthorsMihaylov DB / Malinauskas T / Aricescu AR
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.6 Å
Structure data

50377

9ffx

EMDB-50377, PDB-9ffx:
Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the short-lived asymmetric bound-closed state
Method: EM (single particle) / Resolution: 3.6 Å

Chemicals

ChemComp-ABU:
GAMMA-AMINO-BUTANOIC ACID

Source
  • homo sapiens (human)
  • lama glama (llama)
KeywordsMEMBRANE PROTEIN / GABA / neurotransmission / gating cycle / time-resolved cryo-EM

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