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TitleX-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in complex with an inhibitor and MgATP
Journal, issue, pagesTo be Published
Publish dateJul 24, 2012 (structure data deposition date)
AuthorsKudo, N. / Kato, R. / Wakatsuki, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-3vvh:
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in complex with an inhibitor and MgATP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-4BM:
N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / kinase domain / kinase / TRANSFERASE-TRANSFERASE INHIBITOR complex

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