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TitleCrystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase in the Complex with Methotrexate from Campylobacter jejuni
Journal, issue, pagesTo Be Published
Publish dateMay 11, 2018 (structure data deposition date)
AuthorsKim, Y. / Makowska-Grzyska, M. / Maltseva, N. / Grimshaw, S. / Joachimiak, A. / Center for Structural Genomics of Infectious Diseases (CSGID)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-6deb:
Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase in the Complex with Methotrexate from Campylobacter jejuni
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-GUN:
GUANINE

ChemComp-K:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-MTX:
METHOTREXATE / chemotherapy*YM

ChemComp-DTT:
2,3-DIHYDROXY-1,4-DITHIOBUTANE

ChemComp-HOH:
WATER

Source
  • campylobacter jejuni subsp. jejuni serotype o:2 (strain atcc 700819 / nctc 11168) (Campylobacter)
KeywordsOXIDOREDUCTASE / MTHFDC / alpha-beta-fold / Structural Genomics / Center for Structural Genomics of Infectious Diseases / CSGID

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