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TitleCrystal structure of the human METTL3-METTL14 complex bound to Compound 19 (ADO_AE_009)
Journal, issue, pagesTo Be Published
Publish dateMar 30, 2021 (structure data deposition date)
AuthorsBedi, R.K. / Dolbois, A. / Caflisch, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.47 Å
Structure data

PDB-7o28:
Crystal structure of the human METTL3-METTL14 complex bound to Compound 19 (ADO_AE_009)
Method: X-RAY DIFFRACTION / Resolution: 2.47 Å

Chemicals

ChemComp-UZB:
9-(2-chloranyl-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl)-4-[4-[(4,4-dimethylpiperidin-1-yl)methyl]phenyl]-1,4,9-triazaspiro[5.5]undecan-2-one

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / METTL3 / Inhibitor / complex

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