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-Structure paper
Title | Characterisation of a novel antimalarial agent targeting haemaglobin digestion that shows cross-species reactivity and excellent in vivo properties. |
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Journal, issue, pages | Mbio, Year 2024 |
Publish date | May 17, 2023 (structure data deposition date) |
Authors | de Koning-Ward, T.F. / Drinkwater, N. / Edgar, R.C.S. / McGowan, S. / Scammells, P.J. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.504 - 2.6 Å |
Structure data | PDB-8svl: PDB-8svm: PDB-8sw9: |
Chemicals | ChemComp-ZN:
ChemComp-WRC: ChemComp-GOL: ChemComp-MG: ChemComp-HOH: ChemComp-CO3: ChemComp-1PE: ChemComp-SO4: |
Source |
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Keywords | HYDROLASE / metallo-exopeptidase; protease inhibitor / malaria / Plasmodium / M1 aminopeptidase / M17 aminopeptidase / metallo-exopeptidase / Leucine Aminopeptidase / aminopeptidase |