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TitleCrystal structure of the influenza virus PA endonuclease in complex with an inhibitor - SRI-29782
Journal, issue, pagesTo Be Published
Publish dateJul 7, 2017 (structure data deposition date)
AuthorsKumar, G. / White, S.W.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.12 Å
Structure data

PDB-5we7:
Crystal structure of the influenza virus PA endonuclease in complex with an inhibitor - SRI-29782
Method: X-RAY DIFFRACTION / Resolution: 2.12 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-G3K:
2-{(2R)-1-[2-(4-chlorophenoxy)-2-methylpropanoyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid

ChemComp-MLT:
D-MALATE

ChemComp-HOH:
WATER

Source
  • influenza a virus
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Virus / Nuclease / Transcription / Cap-snatching / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex

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