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TitleCrystal structure of human carbonic anhydrase isozyme II with 5-(phenylsulfonyl)thiophene-2-sulfonamide
Journal, issue, pagesTo be Published
Publish dateJul 1, 2013 (structure data deposition date)
AuthorsSmirnov, A. / Manakova, E. / Grazulis, S. / Matulis, D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-4lhi:
Crystal structure of human carbonic anhydrase isozyme II with 5-(phenylsulfonyl)thiophene-2-sulfonamide
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-WWL:
5-(phenylsulfonyl)thiophene-2-sulfonamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE/LYASE INHIBITOR / drug design / carbonic anhydrase / benzenesulfonamide / metal-binding / LYASE-LYASE INHIBITOR complex

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