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TitleTHE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000250
Journal, issue, pagesto be published
Publish dateMar 3, 2015 (structure data deposition date)
AuthorsSomers, D.O. / Neu, M. / Stuckey, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.652 Å
Structure data

PDB-4yjv:
THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000250
Method: X-RAY DIFFRACTION / Resolution: 1.652 Å

Chemicals

ChemComp-4DT:
3-[6-({4-[ethyl(1H-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1H-indazol-1-yl]propan-1-ol

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / SYK / NON-RECEPTOR TYROSINE KINASE / SPLEEN TYROSINE KINASE / PHOSPHORYLATION / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX

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