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-Structure paper
Title | Staphylococcus aureus Dihydrofolate Reductase complexed with cyclized alpha-NADPH anomer and 3'-(3-(2,4-diamino-6-ethylpyrimidin-5-yl)prop-2-yn-1-yl)-5'-methoxy-[1,1'-biphenyl]-4-carboxylic acid (UCP1175) |
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Journal, issue, pages | To Be Published |
Publish date | Jan 6, 2016 (structure data deposition date) |
![]() | Reeve, S.M. / Anderson, A.C. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.81 Å |
Structure data | ![]() PDB-5hf2: |
Chemicals | ![]() ChemComp-XNP: ![]() ChemComp-U75: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / NADPH / Propargyl-linked antifolates / Dihydrofolate Reductase / Antibiotics |