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-Structure paper
Title | Crystal structure of binary and ternary complexes of thymidylate synthase (ThyA) from Mycobacterium tuberculosis: insights into the selectivity and mode of inhibition |
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Journal, issue, pages | To be Published |
Publish date | Jan 28, 2011 (structure data deposition date) |
Authors | Reddy, M.C.M. / Bruning, J.B. / Harshbarger, W. / Sacchettini, J.C. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.504 Å |
Structure data | PDB-3qj7: PDB-4fqs: |
Chemicals | ChemComp-UMP: ChemComp-SPM: ChemComp-HOH: ChemComp-LYA: |
Source |
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Keywords | TRANSFERASE / Thymidilate synthase / Structural Genomics / TB Structural Genomics Consortium / TBSGC / TRANSFERASE/TRANSFERASE INHIBITOR / Folate binding / TRANSFERASE-TRANSFERASE INHIBITOR complex |