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TitleTPP-45142, an Anti-HER2 T-cell Engager Designed for Selective HER2-Low Cancer Immune TherapyImmunotherapy
Journal, issue, pagesTo Be Published
Publish dateJan 11, 2025 (structure data deposition date)
AuthorsDe Tavernier E / Kim P / Bruch EM / Cortez-Retamozo V / Rak A / Vintem APB
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.66 - 3.06 Å
Structure data

48606

9mte

EMDB-48606, PDB-9mte:
CryoEM structure of extracellular domain of human HER2 complexed with two nano-bodies 27A05 and 47D05
Method: EM (single particle) / Resolution: 2.66 Å

48615

9mtx

EMDB-48615, PDB-9mtx:
CryoEM structure of extracellular domain of human HER2 complexed with nano-bodies 29E09
Method: EM (single particle) / Resolution: 3.06 Å

Source
  • lama glama (llama)
  • homo sapiens (human)
KeywordsTRANSFERASE/IMMUNE SYSTEM / Nanobodies / VHH / Her2 / Complex / cancer / TRANSFERASE / TRANSFERASE-IMMUNE SYSTEM complex

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