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TitleIntersecting PTMs regulate clearance of pathogenic tau by the ubiquitin ligase CHIP.
Journal, issue, pagesTo Be Published
Publish dateMar 2, 2023 (structure data deposition date)
AuthorsNadel, C.M. / Wucherer, K.N. / Thwin, A. / Southworth, D. / Gestwicki, J.E.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.36823537069 Å
Structure data

PDB-8gck:
Crystal structure of the human CHIP-TPR domain in complex with a 6mer acetylated tau peptide
Method: X-RAY DIFFRACTION / Resolution: 1.36823537069 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / E3 ligase / ligand / TPR domain

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