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Structure paper

TitleEGFR(T790M/V948R) kinase in complex with benzimidazole allosteric inhibitor
Journal, issue, pagesTo be published
Publish dateFeb 24, 2023 (structure data deposition date)
AuthorsBeyett, T.S. / Eck, M.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.59 Å
Structure data

PDB-8gb4:
EGFR(T790M/V948R) kinase in complex with benzimidazole allosteric inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.59 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM


ChemComp, No image

ChemComp-YW5:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / EGFR / kinase / allosteric / inhibitor / cancer

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