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Structure paper

TitleT-to-R switch of muscle FBPase involves extreme changes of secondary and quaternary structure
Journal, issue, pagesTo Be Published
Publish dateNov 17, 2015 (structure data deposition date)
AuthorsBarciszewski, J. / Wisniewski, J. / Kolodziejczyk, R. / Dzugaj, A. / Jaskolski, M. / Rakus, D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.92 Å
Structure data

PDB-5et8:
Human muscle fructose-1,6-bisphosphatase in active R-state in complex with fructose-6-phosphate
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

Chemicals

ChemComp-F6P:
6-O-phosphono-beta-D-fructofuranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / carbohydrate metabolism / glyconeogenesis / muscle / FBPase / R-state / Leucine lock / Asp187 / fructose-6-phosphate

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