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TitleA crystal structure of heme-dependent tyrosine hydroxylase complexed with a substrate analog, 3-(4-hydroxyphenyl)propionic acid
Journal, issue, pagesTo Be Published
Publish dateJan 13, 2024 (structure data deposition date)
AuthorsTraore, E. / Wang, Y. / Liu, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.56 Å
Structure data

PDB-8vmk:
A crystal structure of heme-dependent tyrosine hydroxylase complexed with a substrate analog, 3-(4-hydroxyphenyl)propionic acid
Method: X-RAY DIFFRACTION / Resolution: 1.56 Å

Chemicals

ChemComp-HPP:
HYDROXYPHENYL PROPIONIC ACID

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • streptomyces sclerotialus (bacteria)
KeywordsOXIDOREDUCTASE/INHIBITOR / tyrosine hydroxylase / heme enzyme / binary complex / OXIDOREDUCTASE / OXIDOREDUCTASE-INHIBITOR complex

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