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Structure paper

TitleAutoinhibited BRAF:(14-3-3)2:MEK complex from Insect cells
Journal, issue, pagesTo Be Published
Publish dateApr 4, 2025 (structure data deposition date)
AuthorsMartinez Fiesco JA / Zhang P
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.83 Å
Structure data

70053

9o2z

EMDB-70053, PDB-9o2z:
Autoinhibited BRAF:(14-3-3)2:MEK complex from Insect cells
Method: EM (single particle) / Resolution: 3.83 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CHU:
N-(3-fluoro-4-{[4-methyl-2-oxo-7-(pyrimidin-2-yloxy)-2H-chromen-3-yl]methyl}pyridin-2-yl)-N'-methylsulfuric diamide

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / B-Raf / MEK / 14-3-3 / B-Raf complex / B-Raf monomer / Inactive B-Raf / Serine/threonine-protein kinase B-raf / RBD / SIGNALING PROTEIN-TRANSFERASE complex

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