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Structure paper

TitleDiheteromeric GluN1/GluN2A (M817V), in complex with glycine, glutamate, and GNE-4123
Journal, issue, pagesTo Be Published
Publish dateJun 11, 2024 (structure data deposition date)
AuthorsJalali-Yazdi F / Kim J / Gouaux E
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.99 Å
Structure data

45285

9c7r

EMDB-45285, PDB-9c7r:
Diheteromeric GluN1/GluN2A (M817V) in digitonin complexed with glycine, glutamate, and GNE-4123
Method: EM (single particle) / Resolution: 3.99 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • rattus norvegicus (Norway rat)
  • aequorea victoria (jellyfish)
KeywordsTRANSPORT PROTEIN / ion channel / NMDA / positive allosteric modulator / pre-open pore conformation

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