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Structure paper

TitleCrystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target
Journal, issue, pagesProteins, Year 2011
Publish dateJan 5, 2011 (structure data deposition date)
AuthorsReddy, M.C.M. / Bruning, J.B. / Thurman, C. / Ioerger, T.R. / Sacchettini, J.C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 - 2.1 Å
Structure data

PDB-3q7u:
Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) complexed with CTP
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3q80:
Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) Complexed with CDP-ME
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-CTP:
CYTIDINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-CDM:
4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL

ChemComp-CL:
Unknown entry

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsTRANSFERASE / TB Structural Genomics Consortium / TBSGC / Rossmann fold / 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase

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