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Structure paper

TitleStructural studies of aminoglycoside antibiotics G418 and its derivatives with readthrough activities
Journal, issue, pagesTo Be Published
Publish dateJul 11, 2017 (structure data deposition date)
AuthorsKanazawa, H. / Tsurumi, N. / Baasov, T. / Kondo, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.5 - 3.008 Å
Structure data

PDB-5xz1:
Crystal structure of the Homo Sapiens cytoplasmic ribosomal decoding site in complex with G418
Method: X-RAY DIFFRACTION / Resolution: 3.008 Å

PDB-5z71:
Crystal structure of the Homo Sapiens cytoplasmic ribosomal decoding site in complex with G418 (P21212 form)
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-GET:
GENETICIN / antibiotic*YM

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsRNA / ribosome / decoding site / G418

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