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TitleCrystal Structure of Activin Receptor Type-Iia (Acvr2A) Kinase Domain in Complex with a Beta- Carboline Inhibitor
Journal, issue, pagesTo be Published
Publish dateMay 3, 2012 (structure data deposition date)
AuthorsWilliams, E. / Chaikuad, A. / Canning, P. / Mahajan, P. / Cooper, C.D.O. / Beltrami, A. / Krojer, T. / Huber, K. / Bracher, F. / von Delft, F. ...Williams, E. / Chaikuad, A. / Canning, P. / Mahajan, P. / Cooper, C.D.O. / Beltrami, A. / Krojer, T. / Huber, K. / Bracher, F. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Bountra, C. / Bullock, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-4asx:
Crystal structure of Activin receptor type-IIA (ACVR2A) kinase domain in complex with dihydro-Bauerine C
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-6OJ:
7,8-bis(chloranyl)-9-methyl-3,4-dihydro-2H-pyrido[3,4-b]indol-1-one

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / PROTEIN KINASE

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