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IF

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Structure paper

TitleExpanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods
Journal, issue, pagesTo Be Published
Publish dateDec 13, 2019 (structure data deposition date)
AuthorsPhan, J. / Fesik, S.W.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.799 Å
Structure data

PDB-6v9o:
Expanding the Chemical Landscape of SOS1 Activators Using Fragment Based Methods
Method: X-RAY DIFFRACTION / Resolution: 1.799 Å

Chemicals

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-QTA:
3-(phenylsulfonyl)benzene-1-sulfonamide

ChemComp-FMT:
FORMIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Ras / SOS / inhibitor / ONCOPROTEIN / Protein-protein complex / MAPK

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