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Structure paper

TitleCrystal structure of human dihydroorotate dehydrogenase (DHODH) with DHO1B0033
Journal, issue, pagesTo be Published
Publish dateJul 21, 2013 (structure data deposition date)
AuthorsZhu, L. / Li, H. / Ren, X. / Zhu, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.07 Å
Structure data

PDB-4ls0:
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH01B0033
Method: X-RAY DIFFRACTION / Resolution: 2.07 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-ORO:
OROTIC ACID

ChemComp-SO4:
SULFATE ION

ChemComp-B3B:
2-{(E)-[2-(4-phenyl-1,3-thiazol-2-yl)hydrazinylidene]methyl}benzaldehyde

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / oxidoreductase / FMN binding / mitochondria inner membrane / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex

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