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TitleInhibitor induced structural effects involving Phe327 in AGC kinases
Journal, issue, pagesTo Be Published
Publish dateFeb 7, 2017 (structure data deposition date)
AuthorsAlam, K.A. / Engh, R.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.088 Å
Structure data

PDB-5n23:
Protein kinase A mutants as surrogate model for Aurora B with AT9283 inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.088 Å

Chemicals

ChemComp-35R:
1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / AT9283 / Surrogate kinase

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