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TitleStructure-Guided Design of Picomolar-level Macrocyclic TRPC5 Channel Inhibitors with Antidepressant Activity
Journal, issue, pagesTo Be Published
Publish dateMay 27, 2025 (structure data deposition date)
AuthorsChe T / Zhang J / Xiong B / Cheng XY
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.23 Å
Structure data

64801

9v6j

EMDB-64801, PDB-9v6j:
Structure-Guided Design of Picomolar-level Macrocyclic TRPC5 Channel Inhibitors with Antidepressant Activity
Method: EM (single particle) / Resolution: 3.23 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

PDB-1eh7:
METHYLATED HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE

Source
  • Homo sapiens (human)
  • mus musculus (house mouse)
KeywordsMEMBRANE PROTEIN / ion channel

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