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Structure paper

TitleEfficient Synthesis of Glycodiversified Nucleoside Analogues by a Thermophilic Promiscuous Glycosyltransferase
Journal, issue, pagesAcs Catalysis, Vol. 15, Page 1217-1229, Year 2025
Publish dateSep 20, 2024 (structure data deposition date)
AuthorsWang, Z. / Li, J. / Wang, X. / Jin, B. / Zhou, L. / Zhao, Z. / Gu, M. / Song, X. / Wang, J. / Deng, Z. ...Wang, Z. / Li, J. / Wang, X. / Jin, B. / Zhou, L. / Zhao, Z. / Gu, M. / Song, X. / Wang, J. / Deng, Z. / Wu, S. / Zhang, Z. / Chen, W.
External linksAcs Catalysis / Search PubMed
MethodsX-ray diffraction
Resolution2.2 - 2.4 Å
Structure data

PDB-9jma:
Crystal structure of glycosyltransferase AvpGT
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-9jn3:
Crystal structure of AvpGT in complex with Ara-A
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-UPG:
URIDINE-5'-DIPHOSPHATE-GLUCOSE

ChemComp-RAB:
2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL / antivirus*YM

Source
  • streptomyces sp. avp053u2 (bacteria)
KeywordsTRANSFERASE / glycosyltransferase

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