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Structure paper

TitleStructure-based conversion of a promiscuous inhibitor to a selective stabilizer of protein-protein interactions
Journal, issue, pagesTo Be Published
Publish dateMar 24, 2020 (structure data deposition date)
AuthorsSijbesma, E. / Visser, E.J. / Plitzko, K. / Thiel, P. / Milroy, L.G. / Kaiser, M. / Brunsveld, L. / Ottmann, C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-6ye9:
Small-molecule inhibitor of 14-3-3 protein-protein interactions
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-OO8:
[2-[2-oxidanylidene-2-[(phenylmethyl)amino]ethoxy]phenyl]phosphonic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / 14-3-3 / Inhibitor / Protein-protein interaction / small molecule

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