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Structure paper

TitleMolecular Basis for Peptide Nitration by a Novel Cytochrome P450 Enzyme in RiPP Biosynthesis
Journal, issue, pagesAcs Catalysis, Page 10391-10404, Year 2025
Publish dateOct 3, 2024 (structure data deposition date)
AuthorsNolan, K. / Usai, R. / Li, B. / Jordan, S. / Wang, Y.
External linksAcs Catalysis / Search PubMed
MethodsX-ray diffraction
Resolution1.51 - 2.03 Å
Structure data

PDB-9duj:
Crystal structure of RufO in complex with (Nle)RYLH
Method: X-RAY DIFFRACTION / Resolution: 1.51 Å

PDB-9eby:
Crystal structure of RufO in complex with MRYLH
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-CL:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • streptomyces atratus (bacteria)
KeywordsOXIDOREDUCTASE / Rufomycin biosynthesis / cytochrome P450 enzyme / RiPP-producing enzyme / nitrating heme enzyme / peptide bound

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