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Structure paper

TitleDiffusing protein binders to intrinsically disordered proteins
Journal, issue, pagesTo Be Published
Publish dateJun 20, 2024 (structure data deposition date)
AuthorsLiu, C. / Bera, A.K. / Baker, D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.87 - 2.4 Å
Structure data

PDB-9cc5:
De novo design of high-affinity protein binders to bio active peptide Amylin
Method: X-RAY DIFFRACTION / Resolution: 1.87 Å

PDB-9cc6:
De novo design of high-affinity protein binders to RNA binding domain of G3bp1
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-9nzh:
Crystal Structure of Amylin-NHO-18 binder complex
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

Source
  • synthetic construct (others)
  • homo sapiens (human)
KeywordsDE NOVO PROTEIN / protein design / diffusion / deep learning / binders / IDP / IDR / Amyloid / phase separation

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