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TitleBiophysical and Structural Characterization of a Novel Class of Influenza Virus Inhibitors
Journal, issue, pagesTo be Published
Publish dateAug 17, 2011 (structure data deposition date)
AuthorsEdavettal, S.C. / Pearce, B.C. / Lewis, H.A. / Schneeweis, L. / Deminie, C. / Discotto, L. / Carpenter, B. / Yanchunas, J. / Langley, D.R. / Metzler, W. ...Edavettal, S.C. / Pearce, B.C. / Lewis, H.A. / Schneeweis, L. / Deminie, C. / Discotto, L. / Carpenter, B. / Yanchunas, J. / Langley, D.R. / Metzler, W. / Gao, M. / Poss, M.A. / Maskos, K. / Mortl, M. / Keifersauer, R. / Steinbacher, S. / Healy, M. / Phillip, T. / Zoeckler, M. / Schartman, R. / McAuliffe, B. / Minassian, B.F. / Shi, S. / Zhu, S. / Pendri, A. / Li, G. / Sinz, M. / Meanwell, N.A. / Krystal, M. / Gerritz, S.W. / Cianci, C. / Baldwin, B.T. / Bryson, J.W. / McDonnell, P.A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-3tg6:
Crystal Structure of Influenza A Virus nucleoprotein with Ligand
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-0MM:
[4-(2-chloro-4-nitrophenyl)piperazin-1-yl][3-(2-chloropyridin-3-yl)-5-methyl-1,2-oxazol-4-yl]methanone

ChemComp-HOH:
WATER

Source
  • influenza a virus
KeywordsVIRAL PROTEIN/INHIBITOR / Influenza nucleoprotein / VIRAL PROTEIN-INHIBITOR complex

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