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Structure paper

TitleHigh resolution X-ray structure of glucagon and selected stereo-inversed analogs in novel crystallographic packing arrangement.
Journal, issue, pagesTo Be Published
Publish dateJun 25, 2019 (structure data deposition date)
AuthorsMroz, P.A. / Gonzalez-Gutierrez, G. / DiMarchi, R.D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.1 - 1.99 Å
Structure data

PDB-6phi:
Crystal structure of native glucagon in space group I41 at 1.1 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.1 Å

PDB-6phj:
Crystal structure of native glucagon in space group P213 at 1.99 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

PDB-6phk:
Crystal structure of glucagon analog with mono-stereoinversion at position 21 (D-Asp21) in space group I41 at 1.18 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.18 Å

PDB-6phl:
Crystal structure of glucagon analog with mono-stereoinversion at position 23 (D-Val23) in space group I41 at 1.44 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.443 Å

PDB-6phm:
Crystal structure of glucagon analog fully composed of D-amino acids in space group I41 at 1.1 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.1 Å

PDB-6phn:
Crystal structure of glucagon analog composed of D-amino acids with mono-stereoinversion at position 23 (L-Val23) in space group I41 at 1.33 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.33 Å

PDB-6pho:
Crystal structure of glucagon analog with selenomethionine substitutions at position 1 and 27 in space group I41 at 1.42 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.42 Å

PDB-6php:
Crystal structure of glucagon analog with 4-bromo-phenylalanine substitutions at position 6 and 22 in space group I41 at 1.65 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-6phq:
Crystal structure of glucagon analog fully composed of D-amino acids with 4-bromo-D-phenylalanine substitutions at position 6 and 22 in space group I41 at 1.1 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.32 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHORMONE / glucagon / GPCR ligand / peptide hormone

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