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-Structure paper
Title | Inhibition of Small GTPases by Stabilization of the GDP Complex, a Novel Approach applied to Rit1, a Target for Rheumatoid Arthritis |
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Journal, issue, pages | To be Published |
Publish date | May 7, 2013 (structure data deposition date) |
![]() | Shah, D.M. / Kobayashi, M. / Keizers, P.H. / Tuin, A.W. / Ab, E. / Manning, L. / Rzepiela, A.A. / Andrews, M. / Hoedemaeker, F.J. / Siegal, G. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.3 Å |
Structure data | ![]() PDB-4klz: |
Chemicals | ![]() ChemComp-GDP: ![]() ChemComp-MG: ![]() ChemComp-HOH: |
Source |
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![]() | PROTEIN BINDING / small GTPase / molecular switch (GTPase) / GDP/GTP binding / GUANINE NUCLEOTIDE BINDING |