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Structure paper

TitleHierarchical Folding-Upon-Binding of an Intrinsically Disordered Protein
Journal, issue, pagesNat Commun, Year 2025
Publish dateJun 4, 2025 (structure data deposition date)
AuthorsKjaer, L.F. / Ielasi, F.S. / Winbolt, T. / Delaforge, E. / Tengo, M. / Bessa, L.M. / Marino-Perez, L. / Boeri-Erba, E. / Bouvignies, G. / Palencia, A. / Jensen, M.R.
External linksNat Commun / Search PubMed
MethodsX-ray diffraction
Resolution1.248 - 1.854 Å
Structure data

PDB-9rfb:
Crystal Structure of Human Rac1 in Complex with the Scaffold Protein POSH (residues 321-348)
Method: X-RAY DIFFRACTION / Resolution: 1.854 Å

PDB-9rff:
Crystal Structure of Human Rac1 Fused with the Scaffold Protein POSH (residues 319-371)
Method: X-RAY DIFFRACTION / Resolution: 1.248 Å

Chemicals

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

Source
  • homo sapiens (human)
KeywordsHYDROLASE / GTPase GTP/GDP-Binding Nucleotide binding

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