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TitleStructure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor
Journal, issue, pagesFront Immunol, Vol. 12, Page 2260-, Year 2021
Publish dateOct 2, 2020 (structure data deposition date)
AuthorsRonayne, E.K. / Peters, S.C. / Gish, J.S. / Wilson, C. / Spencer, H.T. / Doering, C.B. / Lollar, P. / Spiegel, P.C. / Childers, K.C.
External linksFront Immunol / Search PubMed
MethodsX-ray diffraction
Resolution4.15 Å
Structure data

PDB-7kbt:
Factor VIII in complex with the anti-C2 domain antibody, G99
Method: X-RAY DIFFRACTION / Resolution: 4.15 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CU:
COPPER (II) ION

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

Source
  • sus scrofa (pig)
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsBLOOD CLOTTING/Immune System / Antibody / inhibitor / BLOOD CLOTTING / BLOOD CLOTTING-Immune System complex

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