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TitleSmall-molecule Allosteric Regulation Mechanism of SHP2
Journal, issue, pagesTo Be Published
Publish dateSep 17, 2022 (structure data deposition date)
AuthorsLuo, Y. / Zhu, J. / Yu, K. / Liu, B.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-8gww:
Small-molecule Allosteric Regulation Mechanism of SHP2
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-KID:
2-[4-(aminomethyl)-4-methyl-piperidin-1-yl]-5-[2,3-bis(chloranyl)phenyl]-3-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-one

Source
  • homo sapiens (human)
KeywordsONCOPROTEIN/INHIBITOR / phosphatase / ONCOPROTEIN-INHIBITOR COMPLEX

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