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TitleFrameshift mutations in genes encoding PBP3 and PBP4 trigger an unusual, extreme beta-lactam resistance phenotype in Burkholderia multivorans
Journal, issue, pagesTo Be Published
Publish dateOct 29, 2020 (structure data deposition date)
AuthorsNukaga, M. / Becka, S.A. / Zeiser, E.T. / Hoshino, Y. / LiPuma, J.J. / Papp-Wallace, K.M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.2 Å
Structure data

PDB-7ddm:
Crystal Structure of PenA39 beta-Lactamase
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

Chemicals

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • burkholderia multivorans cgd2 (bacteria)
  • synthetic construct (others)
KeywordsHYDROLASE / beta-lactamase

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