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TitleFlipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides
Journal, issue, pagesAcs Catalysis, Vol. 13, Page 4768-4777, Year 2023
Publish dateOct 24, 2022 (structure data deposition date)
AuthorsZhou, C. / Chen, X. / Lv, T. / Han, X. / Feng, J. / Liu, W. / Wu, Q. / Zhu, D.
External linksAcs Catalysis / Search PubMed
MethodsX-ray diffraction
Resolution1.55 - 1.62 Å
Structure data

PDB-8h8y:
Crystal structure of AbHheG from Acidimicrobiia bacterium
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-8hqp:
Crystal structure of AbHheG mutant from Acidimicrobiia bacterium
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • acidimicrobiia bacterium (bacteria)
KeywordsOXIDOREDUCTASE / catalysis / protein / mutant

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