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TitleCrystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-47
Journal, issue, pagesTo Be Published
Publish dateMay 21, 2024 (structure data deposition date)
AuthorsWang, G.Q. / Amrhein, J.A. / Knapp, S. / Structural Genomics Consortium (SGC)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-9fet:
Crystal Structure of Human Vaccinia-related kinase 2 (VRK-2) bound to JA-47
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-REB:
[4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}amino)phenyl]acetonitrile

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Kinase / VRK2 / Inhibitor / JA-296

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