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TitleSTRUCTURE OF LIGAND BOUND CD33 RECEPTOR ASSOCIATED WITH ALZHEIMER'S DISEASE
Journal, issue, pagesTo Be Published
Publish dateMar 27, 2016 (structure data deposition date)
AuthorsDodd, R.B. / Meadows, W. / Qamar, S. / Johnson, C.M. / Kronenberg-Versteeg, D. / St George-Hyslop, P.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.48 - 2.66 Å
Structure data

PDB-5j06:
Structure of the immune receptor CD33 in complex with 3'-sialyllactose
Method: X-RAY DIFFRACTION / Resolution: 2.66 Å

PDB-5j0b:
Structure of the immune receptor CD33 in complex with 6'-sialyllactose
Method: X-RAY DIFFRACTION / Resolution: 2.48 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PG0:
2-(2-METHOXYETHOXY)ETHANOL / inhibitor, precipitant*YM

ChemComp-SIA:
N-acetyl-alpha-neuraminic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / IMMUNE RECEPTOR / SIGLEC / IG-LIKE / SIALIC-ACID BINDING

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