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-Structure paper
Title | Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with 2-({[4-(Trifluoromethoxy)Phenyl]Sulfonyl}Amino)Ethyl Dihydrogen Phosphate (F9F) inhibitor in the alpha site and ammonium ion in the metal coordination site. |
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Journal, issue, pages | To Be Published |
Publish date | Jan 25, 2015 (structure data deposition date) |
Authors | Hilario, E. / Caulkins, B.G. / Young, R.P. / Niks, D. / Dunn, M.F. / Mueller, L.J. / Fan, L. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.65 Å |
Structure data | PDB-4xug: |
Chemicals | ChemComp-F9F: ChemComp-PLP: ChemComp-NH4: ChemComp-EDO: ChemComp-HOH: |
Source |
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Keywords | LYASE/LYASE INHIBITOR / carbon-oxygen lyase / hydro-lyase / tryptophan biosynthesis / Salmonella typhimurium / F9F / inhibitor / allosteric enzyme / aromatic amino acid biosynthesis / pyridoxal phosphate / LYASE-LYASE INHIBITOR complex |