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TitleKinase Domain of Human Ephrin Type-A Receptor 3 (Epha3) in Complex with ALW-II-38-3.
Journal, issue, pagesTo be Published
Publish dateJul 30, 2008 (structure data deposition date)
AuthorsWalker, J.R. / Syeda, F. / Gray, N. / Mansoor, W. / Mackenzie, F. / Bountra, C. / Weigelt, J. / Arrowsmith, C.H. / Edwards, A.M. / Bochkarev, A. / Dhe-Paganon, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-3dzq:
Human EphA3 kinase domain in complex with inhibitor AWL-II-38.3
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-IFC:
N-[2-methyl-5-({[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]carbonyl}amino)phenyl]isoxazole-5-carboxamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / RECEPTOR TYROSINE KINASE / STRUCTURAL GENOMICS CONSORTIUM / SGC / ATP-BINDING / MEMBRANE / NUCLEOTIDE BINDING / PHOSPHORYLATION / TRANSMEMBRANE / TYROSINE-PROTEIN KINASE / INHIBITOR-COMPLEX / Nucleotide-binding / Phosphoprotein

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